金长江

2010-09-06来源:中科大生命科学院

博士,副教授,硕士生导师。

2005年毕业于中国科学技术大学并获生物学博士学位。其后在合肥微尺度物质科学国家实验室从事博士后研究。2009年作为优秀人才引进被聘为中国科学技术大学生命科学学院副教授。广泛从事了细胞膜与细胞骨架动力学、细胞有丝分裂调控及蛋白质修饰调控的生物学研究。自2003年起,发表SCI 文章20余篇,其中部分刊登在Oncogene, J. Biol. Chem.等国际知名学术期刊上。

 

主要研究兴趣:

1) 蛋白质翻译后修饰调控

2) 细胞周期调控

3) 膜泡运输

 

主要代表性论文:

1.Yu J, Lan J, Wang C, Wu Q, Zhu Y, Lai X, Sun J, Jin C¶, Huang H¶. PML3 interacts with TRF1 and is essential for ALT-associated PML bodies assembly in U2OS cells. Cancer Lett. 2009 Nov 7. [Epub ahead of print] (¶ Corresponding author)

2.Yuan K, Li N, Jiang K, Zhu T, Huo Y, Wang C, Lu J, Shaw A, Thomas K, Zhang J, Mann D, Liao J, Jin C¶, Yao X¶. PinX1 is a novel microtubule-binding protein essential for accurate chromosome segregation.J Biol Chem 2009 284(34):23072-23082 (¶ Corresponding author)

3.Yuan K, Li N, Huo Y, Yan F, Yang Y, Ward T, Jin C¶, Yao X¶. Recruitment of separase to mitotic chromosomes is regulated by Aurora B.Cell Cycle 2009 8(9):1433-43. (¶ Corresponding author)

4.Du J, Cai X, Yao J, Ding X ¶, Wu Q, Pei S, Jiang K, Zhang Y, Wang W, Shi Y, Lai Y, Shen J, Teng M, Huang H, Fei Q, Reddy ES, Zhu J, Jin C ¶, and Yao X. ¶ 2008. The mitotic checkpoint kinase NEK2A regulates kinetochore microtubule attachment stability. Oncogene 2008 27 (29): 4107-4114. (¶ Corresponding author)

5.Cheng Z, Ke Y, Ding X, Wang F, Wang H, Wang W, Ahmed K, Liu Z, Xu Y, Aikhionbare F, Yan H, Liu J, Xue Y, Yu J, Powell M, Liang S, Wu Q, Reddy SE, Hu R, Huang H, Jin C¶, and Yao X. ¶ 2008.Functional characterization of TIP60 sumoylation in UV-irradiated DNA damage response.Oncogene 27, 931-941. (¶ Corresponding author)

6.Yu J, Lan J, Zhu Y, Li X, Lai X, Xue Y, Jin C¶, and Huang H. ¶ The E3 ubiquitin ligase HECTD3 regulates ubiquitination and degradation of Tara. 2008. Biochem Biophys Res Commun367, 805–812. (¶ Corresponding author)

7.Liu D, Ding X, Du J, Cai X, Huang Y, Ward T, Yang Y, Hu R, Jin C¶, and Yao X. ¶ 2007. Human NUF2 Interacts with Centromere-associated Protein E and is essential for a stable spindle microtubule-kinetochore attachment. J Biol Chem 282, 21415-21424. (¶ Corresponding author)

8.Jin C, Cai X, Ma H, Xue Y, Yao J, and Yao X. 2007. An efficient site-directed mutagenesis method for ColE1-type ori plasmid. Analytical Biochemistry 363, 151–153.

9.Jin C, Ge L, Ding X, Chen Y, Zhu H, Ward T, Wu F, Cao X, Wang Q, Yao X. 2006. PKA-mediated protein phosphorylation regulates Ezrin-WWOX interaction. Biochem Biophys Res Commun341, 784-791.

10.Jin C, Zhang Y, Zhu H, Ahmed K, Fu C, and Yao X. 2005. Human Yip1A specifies the localization of Yif1 to the Golgi apparatus. Biochem Biophys Res Commun334, 16–22.

 

联系方式:

Email: jincj@ustc.edu.cn; 电话:0551-63607821

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